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Bio 220 Lecture 11: Coordination of complex organisms

Campbell, 5th, pp. 778-790, 993-996, 188-190, 893-896

I. Communication between organ systems

A complex, multicellular organism requires communication between different cells and tissues.

It is necessary for:
- coordination of different organ systems
- ability to respond to altered situations
- maintenance of homeostasis

A. Homeostasis40.11
Homeostasisis the steady-state physiological condition of the body of an animal. The internal environment is notconstant; it is a dynamic equilibriumwhere changes occur, but they are countered in such a way as to keep them within the acceptable range.
This requires three components:

1. Receptor- detects change in environment 2. Control center- processes information 3. Effector- responds to change

Humans use these mechanisms to regulate temperature (37ºC), blood glucose (800 mg/ml), O2 (100 mm Hg), CO2 ( 40mm Hg), Na+ (142 mEg/L) and K+ (4 mEq/L).

D. Negative vs Positive feedback40.12 Negative feedback: a change in a variable triggers a response that counteractsthat change. For example, a thermostat senses that the temperature has fallen below the set point and activates the furnace to heat the room.