|
|
|
Human kidney
group discussion
Notes:
Read Campbell, 5th, pp. 878-889, Figures 44.13, 44.14,
44.18. 44.19, 44.20 (Campbell, 4th, pp. 886-895, Figures
40.4, 40.9-40.13, pp. 924-925)
also see pp. 900-901 for
release of ADH by hypothalamus and pituitary
Diabetes: high rate of urine production
diuretic: drug that causes increase in rate of urine
production
The
mammalian kidney is uniquely adapted to conserve water while
secreting and reabsorbing solutes. Blood pressure forces
water and solutes from the blood into Bowman's capsule. This
filtrate is similar in composition to blood plasma without
the proteins. The filtrate passes through the nephron and
empties into the collecting duct; in the process it is
concentrated and the ionic composition drastically altered
to form urine. The different regions of the juxtamedullary
nephron outlined below differ greatly in their active and
passive transport of solutes and water. Furthermore, these
transport properties can be changed in response to the water
and ionic balance in the blood and under the influence of
hormones. The key to understanding kidney function lies in
understanding these transport properties.
Part
1
Each group should assign one person to thoroughly
research one of the following regions. Pay attention to
which substances are being moved in and out, the type of
transport that is responsible for the movement of each, and
which of the basic processes (filtration, reabsorption,
secretion and concentration) is occuring in your region. Be
prepared to explain your region to the group on
Friday.
|
|
1 2 3
4 5
